What if a patient needs more time to decide but cannnot come back into clinic for the research-only visit?

This scenario might occur at clinics that serve rural populations but is likely to be rare otherwise. Like the pending MRI cases discussed in C3, these patients can be consented and provisionally enrolled if they meet all eligibility criteria. Perform all of the usual enrollment procedures with the patient except for randomization. Follow up with the patient about a week later and ask for their final decision. If the patient does want to participate, you may then randomize them over the phone.